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THE DOUBLE HELIX BY JAMES WATSON PDF

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by James D. Watson I was much pleased when Watson asked me to write . curiosity about how the double helix was found, and to them an incomplete. The annotated and illustrated double helix / James D. Watson ; edited by Alexander of Watson, Crick, and Wilkins, but of Franklin, Linus Pauling, and others as. (The Double Helix Revisited. -Francis Crick and James Watson talk to Paul Vaughan about their discovery of the molecular structure of DNA. "VAUGHAN: James.


The Double Helix By James Watson Pdf

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About Books [PDF] The Double Helix: A Personal Account of the Discovery of the Structure of DNA by James D. Watson BEST BOOKS: The. The double helix: a personal account of the discovery of the structure of DNA by James D. Watson; 1 edition; First published in ; Subjects: Accessible book. PDF | On Apr 1, , Jonathan Wayne Riddle and others published A Book Report on The Double Helix () by James Watson.

About James D. Watson James D. Watson is an American geneticist, molecular biologist, and zoologist, a co-discoverer of the structure of DNA with Francis Crick.

He resigned after making one possibly racist remark. This structure has novel features which are of considerable biological interest. Because what we just described was the article and the day the world first saw the double helical structure of the DNA we have grown accustomed to in the meantime.

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So, the autumn of , he went to Cambridge University and joined the group working in the Cavendish Laboratory. Officially — to work on three-dimensional structures of proteins.

Unofficially — to make a discovery which will grant him a Nobel. You think he may have overreacted? Himself included. Anyway, Watson and Crick may have had dreams of greatness, but neither of them had any clue how they were supposed to be the first to discover the structure of DNA when everybody who meant something in the world of biochemistry at the day was trying to achieve the same thing.

To put it mildly, the odds were against them. In London, Wilkins was working with Rosalind Franklin, gathering and analyzing data.

But, you know how it goes: scarcity breeds invention — especially after hours. And, as Machiavelli once said , the end justifies the means.

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At that time he was thirty-five, yet almost totally unknown. Although some of his closest colleagues realized the value of his quick, penetrating mind and frequently sought his advice, he was often not appreciated, and most people thought he talked too much. Leading the unit to which Francis belonged was Max Perutz, an Austrian-born chemist who came to England in He had been collecting X-ray diffraction data from hemoglobin crystals for over ten years and was just beginning to get somewhere.

Helping him was Sir Lawrence Bragg, the director of the Cavendish. For almost forty years Bragg, a Nobel Prize winner and one of the founders of crystallography, had been watching X-ray diffraction methods solve structures of ever-increasing difficulty.

The more complex the molecule, the happier Bragg became when a new method allowed its elucidation.

Thus in the immediate postwar years he was especially keen about the possibility of solving the structures of proteins, the most complicated of all molecules. Often, when administrative duties permitted, he visited Perutz' office to discuss recently accumulated X-ray data. Then he would return home to see if he could interpret them.

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Somewhere between Bragg the theorist and Perutz the experimentalist was Francis, who occasionally did experiments but more often was immersed in the theories for solving protein structures.

Often he came up with something novel, would become enormously excited, and immediately tell it to anyone who would listen. A day or so later he would often realize that his theory did not work and return to experiments, until boredom generated a new attack on theory. There was much drama connected with these ideas.

This was a highly educated man.

An intelligent man. Surely a man such as that should be held to higher standards and should have been a voice for equality and not one spreading misogynistic ideas? If Franklin had lived it also would have highlighted the quandary over whether or not she would she have been awarded a Nobel prize too?

Undoubtedly her work was a key component in determining the structure of DNA. However, a Nobel Prize can only be awarded to a maximum of three people. Who would have lost out?The C2 symmetry.

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Remarkably, this pairing also gave an explanation of the earlier finding by Erwin Chargaff that the amount of adenine in any DNA sample equalled that of thymine, and similarly for guanine and cytosine. This is discussed in great detail in Wilkins' autobiography.

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The pattern of diffracted waves depends on the particular setting of the crystal relative to the incident X-ray beam. A decade later, cytologist Walther Flemming was studying division in salamander cells by staining them with dyes; he revealed coloured threads that he called chromatin chromosomes.

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